WebMay 4, 2024 · Total RNA from shYTHDF2 and NTC Hep3B cell subclones was extracted and subjected to RNA sequencing. However, no difference in NANOG, SOX2, OCT4, and KLF4 … WebOct 12, 2024 · Messenger RNA m 6 A modification is shown to regulate local translation in axons. However, how the m 6 A codes in axonal mRNAs are read and decoded by the m 6 …

SUMOylation of YTHDF2 promotes mRNA degradation and

Web100 of cultured RGC s treated by shYthdf2 (Fig ure 1C,D ; Figure 1 v figure supplement 1G,H ). In contrast, 101 the dendrite branching of RGCs with YTHDF1 KD using shYthdf1 was not significantly different from 102 control shRNA ( Figure 1 v figure supplement 1 I), while YTHDF3 KD using shYthdf3 caused a slight We analyzed The Cancer Genome Atlas (TCGA) and CHOICE datasets of Chinese patients with NSCLC to evaluate the expression profiles of m6A “write”, “eraser”, and “reader” genes (WERs) in LUAD23. The results showed that in both datasets, the mRNA expression levels of METTL3, VIRMA, RBM15, RBM15B, … See more Next, we investigated the effect of YTHDF2 on the aggressive capacities of LUAD in vitro. Our results showed that the ectopic overexpression of YTHDF2 in A549 … See more Given that YTHDF2 promotes mRNA degradation by targeting m6A-modified mRNAs to processing bodies in the cytoplasm, identifying the key factor that … See more hideaway lakes tornillo texas

Frontiers Identification of Prognostic Model and Biomarkers for ...

WebJan 8, 2024 · shYTHDF2#1-resistant YTHDF2 to the YTHDF2-depleted GSCs rescued the malignant phenotypes of GSCs (Fig. 2 d – h, Supple- mentary Fig. 2h-k), suggesting that … WebNov 18, 2024 · YTHDF2 inhibits IL-11 and Serpin E2 expression in HCC cells. (a) Volcano plots showing up (red) - or down (blue) -regulated genes in SMMC7721-shYTHDF2 versus SMMC7721-shCtrl cells, as assessed by RNA-seq. (b) GO analysis based on the RNA-seq in (A), showing the most significant GO terms and the P values. hideaway lakes valley center