WebMetronidazole and fluconazole inhibit the metabolism of warfarin by blocking cytochrome P-450 2C9 (CYP-2C9), the major metabolic pathway of warfarin, with the end result being dramatic increases in patients' international normalized ratios (INRs) and potentially fatal bleeding. ... Warfarin / adverse effects* Warfarin / pharmacology Substances ... WebNov 4, 2024 · Broccoli, Brussels sprouts, cabbage, kale, spinach. Blood thinners such as warfarin (Coumadin). Foods that contain a lot of vitamin K, such as the greens noted on the left, can reduce the drugs ...
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WebMay 23, 2005 · Background Warfarin is a highly efficacious oral anticoagulant, but its use is limited by a well-founded fear of bleeding. Drug and food interactions are frequently cited as causes of adverse events … WebMar 10, 2016 · Remember that warfarin specifically inhibits vitamin K-dependent clotting factors (II, VII, IX, X, Protein C, Protein S). If there is less vitamin K, there are less of those clotting factors. All of this means that Flagyl can shoot up your patient's … Metronidazole (Flagyl) - This antibiotic is definitely one of the bad boys for … cservice459 outlook.com
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