Cinnamaldehyde cytotoxicity
WebCytotoxicity and effects of curcumin and cinnamaldehyde hybrids on biofilms of oral pathogens . Authors Vanessa Rodrigues Dos Santos 1 , Karina Sampaio Caiaffa 1 , Warlley Campos de Oliveira 1 , Jesse Augusto Pereira 1 , Gabriel Flores Abuna 2 , Carlos Roberto Polaquini 3 , Luís Octávio Regasini 3 , Aimée Maria Guiotti 4 , Cristiane Duque 1 WebCinnamaldehyde (CM) is the active component of the spice cinnamon (Cinnamomum zeylanicum) ( Rao & Gan, 2014 ). This component is widely known for its …
Cinnamaldehyde cytotoxicity
Did you know?
WebCinnamaldehyde is the major active constituents of Cinnamomum verum. Cinnamaldehyde has been widely studied for its various biological activities including … WebJul 10, 2003 · Cinnamaldehyde is an active compound isolated from the stem bark of Cinnamomum cassia,a traditional oriental medicinal herb, which has been shown to …
WebNov 29, 2024 · Additionally, cinnamaldehyde itself, the main chemical agent providing a cinnamon flavor, is highly cytotoxic in in vitrostudies [[20], [21], [22]] and impairs bronchial epithelial cell ciliary motility [23]. One study found cinnamaldehyde in 20 out of 39 e-liquids tested with concentrations ranging from 1.7 × 10−5to 1.1 M [21]. WebCytotoxicity on different cells was detected, followed by the tumor cell uptake tests. The intracellular reactive oxygen species (ROS) changes, mitochondrial functions and activities of caspase-3/-9 in MCF-7 cells were also evaluated, respectively. ... Cinnamaldehyde (CA) is commonly used in the food and beverage production as a flavoring agent ...
WebJan 1, 2010 · Conversely, at sublethal concentrations, these agents induced an adaptive antioxidant response through Nrf2-mediated upregulation of phase II enzymes, including TrxR induction. We conclude from the results obtained that TrxR inactivation contributes at least partly to cinnamaldehyde cytotoxicity. WebJul 16, 2024 · On the other hand, the genotoxicity of perillaldehyde and cinnamaldehyde are potential concerns due to the presence of α and β-unsaturated aldehydes in their structures; these unsaturated aldehydes are electrophilic and can react with electron-rich macromolecules, including DNA, to form DNA adducts [ 8 ].
WebConclusion: Cinnamaldehyde and acrylates exhibited both anti-inflammatory and pro-inflammatory properties, possibly due to their marked ability to act as Michael reaction acceptors, as estimated from the beta-carbon 13 C-nuclear magnetic resonance spectra. …
WebJul 10, 2003 · Using apoptosis analysis, measurement of reactive oxygen species (ROS), and assessment of mitochondrial membrane potentials (DeltaPsim), we show that cinnamaldehyde is a potent inducer of apoptosis and that it transduces the apoptotic signal via ROS generation, thereby inducing mitochondrial permeability transition (MPT) and … cylch meithrin myrddinWebMar 12, 2014 · Carvacrol and trans-cinnamaldehyde reduce Clostridium difficile toxin production and cytotoxicity in vitro Clostridium difficile is a nosocomial pathogen that causes a serious toxin-mediated enteric disease in humans. Reducing C. difficile toxin production could significantly minimize its pathogenicity and improve disease outcomes … cylch meithrin nant dyrysWebLung cancer is a malignant tumor characterized by a rapid proliferation rate, less survivability, high mortality, and metastatic potential. This review focuses on updated research about the clinical application of traditional Chinese medicine (TCM) as an adjuvant therapy to lung cancer treatment and the mechanisms of TCM effect on lung cancer in … cylch meithrin morfa nefynWebApr 11, 2024 · The aim of this study was to evaluate the effect of eight commercially available EO-derived compounds ((R)-(+)-limonene, (S)-(-)-limonene, sabinene, carvacrol, thymol, alpha-pinene, beta-pinene, and cinnamaldehyde) on the bone formation process in vitro to select the most promising natural agents that could potentially be used in the … cylch meithrin nefynWebJan 1, 2004 · Cinnamaldehyde detected in maximum proportion, is known to inhibit various cancer or tumor cell lines [52], and its antibacterial [53] and antifungal [54] properties are … cylch meithrin nant lleucuWebCinnamaldehyde is Generally Recognized As Safe (GRAS) by the Flavoring Extract Manufacturers' Association and is approved for food use (21 CFR 182.60) by the Food … cylch meithrin newportWebFood additives have been used by mankind for centuries. Most food additives are considered safe; however, some are known to be toxic or carcinogenic. Aldehydes occur … cylch meithrin nantgaredig